@article{painter2025cdm,
author = {Jeffery L. Painter and Darmendra Ramcharran and Andrew Bate},
title ={Perspective review: Will generative AI make common data models obsolete in future analyses of distributed data networks?},
journal = {Therapeutic Advances in Drug Safety},
volume = {16},
number = {},
pages = {20420986251332743},
year = {2025},
doi = {10.1177/20420986251332743}
}
@misc{haguinet2025bdb,
author = {Haguinet, F. and Painter, J.L. and Powell, G.E. and Callegaro, A and Bate, A.},
title = {Bayesian dynamic borrowing considering semantic similarity between outcomes for disproportionality analysis in FAERS}},
howpublished = {arXiv preprint arXiv:2504.12052},
year = {2025},
month = {03},
note = {Posted 2025 Apr 16},
doi = {10.48550/arXiv.2504.12052}
}
@misc{painter2025ssm,
author = {Painter, J.L. and Haguinet, F. and Powell, G.E. and Bate, A.},
title = {Ontology-based Semantic Similarity Measures for Clustering Medical Concepts in Drug Safety}},
howpublished = {arXiv preprint arXiv:2503.20737},
year = {2025},
month = {03},
note = {Posted 2025 Mar 27; cited 2025 Mar 28},
doi = {10.48550/arXiv.2503.20737}
}
@article{painter2025automating,
title={Automating pharmacovigilance evidence generation: using large language models to produce context-aware structured query language},
author={Painter, Jeffery L and Chalamalasetti, Venkateswara Rao and Kassekert, Raymond and Bate, Andrew},
journal={JAMIA open},
volume={8},
number={1},
pages={ooaf003},
year={2025},
publisher={Oxford University Press}
}
2025
6.
An Application of Bayesian Modelling for Information Sharing in Safety Signal Detection François Haguinet, Olivia Mahaux, JL Painter, Andrew Bate .
Oral Presentation [1331]. ISPE Annual Meeting, Berlin, Germany, August 24, 2024.
2024
7.
Ontology-based Semantic Similarity Measures in Drug Safety: A Literature Review François Haguinet, JL Painter, and Andrew Bate .
Oral Presentation [967]. ISPE Annual Meeting, Berlin, Germany, August 24, 2024.
@misc{painter2024rshiny,
author = {Painter, Jeffery},
year = {2024},
month = {07},
pages = {},
title = {Developing an R Shiny Interactive Module for Teaching Statistics to High School Students},
doi = {10.13140/RG.2.2.28736.96005}
}
@article{hakim2024need,
title={The Need for Guardrails with Large Language Models in Medical Safety-Critical Settings: An Artificial Intelligence Application in the Pharmacovigilance Ecosystem},
author={Hakim, Joe B and Painter, Jeffery L and Ramcharran, Darmendra and Kara, Vijay and Powell, Greg and Sobczak, Paulina and Sato, Chiho and Bate, Andrew and Beam, Andrew},
journal={arXiv preprint arXiv:2407.18322},
year={2024}
}
@article{minikel2024refining,
title={Refining the impact of genetic evidence on clinical success},
author={Minikel, Eric Vallabh and Painter, Jeffery L and Dong, Coco Chengliang and Nelson, Matthew R},
journal={Nature},
volume={629},
number={8012},
pages={624--629},
year={2024},
publisher={Nature Publishing Group UK London}
}
@inproceedings{painter2023enhancing,
title={Enhancing drug safety documentation search capabilities with large language models: a user-centric approach},
author={Painter, Jeffery L and Mahaux, Olivia and Vanini, Marco and Kara, Vijay and Roshan, Christie and Karwowski, Marcin and Chalamalasetti, Venkateswara Rao and Bate, Andrew},
booktitle={2023 International Conference on Computational Science and Computational Intelligence (CSCI)},
pages={49--56},
year={2023},
organization={IEEE}
}
@article{talekar2023semi,
title={Semi-automation of keratopathy visual acuity grading of corneal events in belantamab mafodotin clinical trials: clinical decision support software},
author={Talekar, Mala K and Painter, Jeffery L and Elizalde, Mica A and Thomas, Michele and Stein, Heather K},
journal={Frontiers in Digital Health},
volume={5},
pages={1138453},
year={2023},
publisher={Frontiers Media SA}
}
@article{painter2023industry,
title={An industry perspective on the use of machine learning in drug and vaccine safety},
author={Painter, Jeffery L and Kassekert, Raymond and Bate, Andrew},
journal={Frontiers in Drug Safety and Regulation},
volume={3},
pages={1110498},
year={2023},
publisher={Frontiers Media SA}
}
@inproceedings{painter2022leveraging,
title={Leveraging Data Pathways for Next Generation Safety Monitoring of Medicines and Vaccines},
author={Painter, Jeffery L and Girard, Laurie and Glaser, Michael and Bate, Andrew},
booktitle={2022 International Conference on Computational Science and Computational Intelligence (CSCI)},
pages={1570--1576},
year={2022},
organization={IEEE}
}
@article{pimenta2022identifying,
title={Identifying barriers to enrollment in patient pregnancy registries: building evidence through crowdsourcing},
author={Pimenta, Jeanne M and Painter, Jeffery L and Gemzoe, Kim and Levy, Roger Abramino and Powell, Marcy and Meizlik, Paige and Powell, Gregory},
journal={JMIR Formative Research},
volume={6},
number={5},
pages={e30573},
year={2022},
publisher={JMIR Publications Inc., Toronto, Canada}
}
@article{powell2022engaging,
title={Engaging patients via online healthcare fora: three pharmacovigilance use cases},
author={Powell, Greg and Kara, Vijay and Painter, Jeffery L and Schifano, Lorrie and Merico, Erin and Bate, Andrew},
journal={Frontiers in Pharmacology},
volume={13},
pages={901355},
year={2022},
publisher={Frontiers Media SA}
}
2022
18.
Artificial Intelligence Based on Machine Learning in Pharmacovigilance: A Scoping Review Kompa, Benjamin and Hakim, Joe B and Palepu, Anil and Kompa, Kathryn Grace and Smith, Michael and Bain, Paul A and Woloszynek, Stephen and Painter, Jeffery L and Bate, Andrew and Beam, Andrew L. Artificial intelligence based on machine learning in pharmacovigilance: a scoping review. Drug Safety, 2022.
@article{kompa2022artificial,
title={Artificial intelligence based on machine learning in pharmacovigilance: a scoping review},
author={Kompa, Benjamin and Hakim, Joe B and Palepu, Anil and Kompa, Kathryn Grace and Smith, Michael and Bain, Paul A and Woloszynek, Stephen and Painter, Jeffery L and Bate, Andrew and Beam, Andrew L},
journal={Drug Safety},
volume={45},
number={5},
pages={477--491},
year={2022},
publisher={Springer}
}
@article{gartland2021developing,
title={Developing crowdsourced training data sets for pharmacovigilance intelligent automation},
author={Gartland, Alex and Bate, Andrew and Painter, Jeffery L and Casperson, Tim A and Powell, Gregory Eugene},
journal={Drug Safety},
volume={44},
pages={373--382},
year={2021},
publisher={Springer}
}
@inproceedings{gemzoe2019crowdsourcing,
title={Crowdsourcing as a novel method to assess the impact of drug exposure on Belimumab pregnancy registry enrollment},
author={Gemzoe, Kim and Painter, Jeffery L and Pimenta, Jeanne and Powell, Greg},
booktitle={PHARMACOEPIDEMIOLOGY AND DRUG SAFETY},
volume={28},
pages={436--436},
year={2019},
organization={WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA}
}
Using Social Listening Data to Monitor Misuse and Nonmedical
Use of Bupropion: A Content Analysis Anderson, Laurie S and Bell, Heidi G and Gilbert, Michael and Davidson, Julie E and Winter, Christina and Barratt, Monica J and Win, Beta and Painter, Jeffery L and Menone, Christopher and Sayegh, Jonathan and others. Using social listening data to monitor misuse and nonmedical use of bupropion: a content analysis. JMIR Public Health and Surveillance, 2017.
@article{anderson2017using,
title={Using social listening data to monitor misuse and nonmedical use of bupropion: a content analysis},
author={Anderson, Laurie S and Bell, Heidi G and Gilbert, Michael and Davidson, Julie E and Winter, Christina and Barratt, Monica J and Win, Beta and Painter, Jeffery L and Menone, Christopher and Sayegh, Jonathan and others},
journal={JMIR Public Health and Surveillance},
volume={3},
number={1},
pages={e6174},
year={2017},
publisher={JMIR Publications Inc., Toronto, Canada}
}
@inproceedings{casperson2016strategies,
title={Strategies for distributed curation of social media data for safety and pharmacovigilance},
author={Casperson, Tim A and Painter, Jeffery L and Dietrich, Juergen},
booktitle={Proceedings of the International Conference on Data Science (ICDATA)},
pages={118},
year={2016},
organization={The Steering Committee of The World Congress in Computer Science, Computer~…}
}
2016
29.
Social Media Listening for Routine Post-Marketing Safety Surveillance Powell, Gregory E and Seifert, Harry A and Reblin, Tjark and Burstein, Phil J and Blowers, James and Menius, J Alan and Painter, Jeffery L and Thomas, Michele and Pierce, Carrie E and Rodriguez, Harold W and others. Social media listening for routine post-marketing safety surveillance. Drug safety, 2016.
@article{powell2016social,
title={Social media listening for routine post-marketing safety surveillance},
author={Powell, Gregory E and Seifert, Harry A and Reblin, Tjark and Burstein, Phil J and Blowers, James and Menius, J Alan and Painter, Jeffery L and Thomas, Michele and Pierce, Carrie E and Rodriguez, Harold W and others},
journal={Drug safety},
volume={39},
pages={443--454},
year={2016},
publisher={Springer}
}
2016
30.
Performance of Stratified and Subgrouped Disproportionality Analyses in Spontaneous Databases Seabroke, Suzie and Candore, Gianmario and Juhlin, Kristina and Quarcoo, Naashika and Wisniewski, Antoni and Arani, Ramin and Painter, Jeffery and Tregunno, Philip and Nor{\'e. Performance of stratified and subgrouped disproportionality analyses in spontaneous databases. Drug safety, 2016.
@article{seabroke2016performance,
title={Performance of stratified and subgrouped disproportionality analyses in spontaneous databases},
author={Seabroke, Suzie and Candore, Gianmario and Juhlin, Kristina and Quarcoo, Naashika and Wisniewski, Antoni and Arani, Ramin and Painter, Jeffery and Tregunno, Philip and Nor{\'e}n, G Niklas and Slattery, Jim},
journal={Drug safety},
volume={39},
pages={355--364},
year={2016},
publisher={Springer}
}
@inproceedings{disantostefano2015safety,
title={Safety Assessment and Selection Bias: Who Uses Social Media to Communicate About Medications?},
author={DiSantostefano, Rachael L and Painter, Jeffery L and Thomas, Michele and Powell, Greg},
booktitle={PHARMACOEPIDEMIOLOGY AND DRUG SAFETY},
volume={24},
pages={547--548},
year={2015},
organization={WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ USA}
}
@inproceedings{thomas2015social,
title={What are People Talking About? Medication Discussions on Social Media},
author={Thomas, Michele and Turnbull, Bradley and Painter, Jeffery and DiSantostefano, Rachael and Powell, Greg},
booktitle={PHARMACOEPIDEMIOLOGY AND DRUG SAFETY},
volume={24},
pages={547--548},
year={2015},
organization={WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ USA}
}
2015
33.
Comparison of Events in Spontaneous Adverse Event Reports To Events Discussed Within Context of Drug Use on Facebook and Twitter Powell, Gregory and Bell, Heidi and Rodriguez, Harold and Thomas, Michele and Painter, Jeffery and Harvey, Cath and Blowers, James and Dasgupta, Nabarun. Comparison of Events in Spontaneous Adverse Event Reports to Events Discussed Within Context of Drug Use on Facebook and Twitter. , 2015.
@inproceedings{powell2015comparison,
title={Comparison of Events in Spontaneous Adverse Event Reports to Events Discussed Within Context of Drug Use on Facebook and Twitter},
author={Powell, Gregory and Bell, Heidi and Rodriguez, Harold and Thomas, Michele and Painter, Jeffery and Harvey, Cath and Blowers, James and Dasgupta, Nabarun},
booktitle={PHARMACOEPIDEMIOLOGY AND DRUG SAFETY},
volume={24},
pages={441--441},
year={2015},
organization={WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ USA}
}
2015
34.
The support of human genetic evidence for approved drug indications Nelson, Matthew R and Tipney, Hannah and Painter, Jeffery L and Shen, Judong and Nicoletti, Paola and Shen, Yufeng and Floratos, Aris and Sham, Pak Chung and Li, Mulin Jun and Wang, Junwen and others. The support of human genetic evidence for approved drug indications. Nature genetics, 2015.
@article{nelson2015support,
title={The support of human genetic evidence for approved drug indications},
author={Nelson, Matthew R and Tipney, Hannah and Painter, Jeffery L and Shen, Judong and Nicoletti, Paola and Shen, Yufeng and Floratos, Aris and Sham, Pak Chung and Li, Mulin Jun and Wang, Junwen and others},
journal={Nature genetics},
volume={47},
number={8},
pages={856--860},
year={2015},
publisher={Nature Publishing Group US New York}
}
2015
35.
A proposed modification to Hy's law and Edish criteria in oncology clinical trials using aggregated historical data Parks, Daniel and Lin, Xiwu and Painter, Jeffery L and Cheng, Jie and Hunt, Christine M and Spraggs, Colin F and Nelson, Jeanenne J and Curtis, Lloyd and Menius, J Alan and Lee, Kwan R. A proposed modification to Hy's law and Edish criteria in oncology clinical trials using aggregated historical data. Pharmacoepidemiology and drug safety, 2013.
@article{parks2013proposed,
title={A proposed modification to Hy's law and Edish criteria in oncology clinical trials using aggregated historical data},
author={Parks, Daniel and Lin, Xiwu and Painter, Jeffery L and Cheng, Jie and Hunt, Christine M and Spraggs, Colin F and Nelson, Jeanenne J and Curtis, Lloyd and Menius, J Alan and Lee, Kwan R},
journal={Pharmacoepidemiology and drug safety},
volume={22},
number={6},
pages={571--578},
year={2013},
publisher={Wiley Online Library}
}
@article{cheng2012predicting,
title={Predicting breast cancer chemotherapeutic response using a novel tool for microarray data analysis},
author={Cheng, Jie and Greshock, Joel and Painter, Jeffery and Lin, Xiwu and Lee, Kwan and Zheng, Shu and Menius, Alan},
journal={Journal of integrative bioinformatics},
volume={9},
number={2},
pages={80--87},
year={2012},
publisher={De Gruyter}
}
2012
37.
Performance of Observational Screening by System Organ Class Powell, Gregory E and Painter, Jeffery L. Performance of observational screening by system organ class. , 2012.
@inproceedings{powell2012performance,
title={Performance of observational screening by system organ class},
author={Powell, Gregory E and Painter, Jeffery L},
booktitle={PHARMACOEPIDEMIOLOGY AND DRUG SAFETY},
volume={21},
pages={231--231},
year={2012},
organization={WILEY PERIODICALS, INC ONE MONTGOMERY ST, SUITE 1200, SAN FRANCISCO, CA~…}
}
@article{lin2012validation,
title={Validation of multivariate outlier detection analyses used to identify potential drug-induced liver injury in clinical trial populations},
author={Lin, Xiwu and Parks, Daniel and Painter, Jeffery and Hunt, Christine M and Stirnadel-Farrant, Heide A and Cheng, Jie and Menius, Alan and Lee, Kwan},
journal={Drug safety},
volume={35},
pages={865--875},
year={2012},
publisher={Springer}
}
@inproceedings{painter2012imaging,
title={An Imaging Framework for the Analysis of Longitudinal High-Dimensional Data},
author={Painter, Jeffery L},
booktitle={Proceedings of the International Conference on Image Processing, Computer Vision, and Pattern Recognition (IPCV)},
pages={1},
year={2012},
organization={The Steering Committee of The World Congress in Computer Science, Computer~…}
}
@inproceedings{painter2011enhanced,
title={Enhanced biomedical taxonomy mapping through use of a semantic measure of proximity},
author={Painter, Jeffery L},
booktitle={Proceedings of the 2011 international conference on information and knowledge engineering, IKE},
pages={18--21},
year={2011}
}
@article{reisinger2010development,
title={Development and evaluation of a common data model enabling active drug safety surveillance using disparate healthcare databases},
author={Reisinger, Stephanie J and Ryan, Patrick B and O'Hara, Donald J and Powell, Gregory E and Painter, Jeffery L and Pattishall, Edward N and Morris, Jonathan A},
journal={Journal of the American Medical Informatics Association},
volume={17},
number={6},
pages={652--662},
year={2010},
publisher={BMJ Group BMA House, Tavistock Square, London, WC1H 9JR}
}
@inproceedings{painter2010containing,
title={Containing the Cloud: Security Issues in a Large Scale Observational Pharmacovigilance Research Project.},
author={Painter, Jeffery},
booktitle={Security and Management},
pages={3--9},
year={2010}
}
@inproceedings{painter2010toward,
title={Toward automating an inference model on unstructured terminologies: OXMIS case study},
author={Painter, Jeffery L},
booktitle={Advances in Computational Biology},
pages={645--651},
year={2010},
organization={Springer}
}
@inproceedings{painter2009codeslinger,
title={Codeslinger: An interactive biomedical ontology browser},
author={Painter, Jeffery L and Flowers, Natalie L},
booktitle={Conference on Artificial Intelligence in Medicine in Europe},
pages={260--264},
year={2009},
organization={Springer}
}
@article{merrill2008construction,
title={Construction and annotation of a UMLS/SNOMED-based drug ontology for observational pharmacovigilance},
author={Merrill, Gary H and Ryan, Patrick B and Painter, Jeffery L},
journal={Methods},
year={2008},
publisher={Citeseer}
}
@inproceedings{ryan2008defining,
title={Defining medical conditions by mapping ICD-9 to MedDRA: a systematic approach to integrating disparate observational data sources for enabling enhanced pharmacovigilance analyses},
author={Ryan, PB and Painter, JL and Merrill, GH},
booktitle={Poster presented at the 44th Annual Drug Information Association Meeting, Boston, MA},
year={2008}
}
@article{merrill2008using,
title={Using SNOMED to normalize and aggregate drug references in the Safetyworks observational pharmacovigilance project},
author={Merrill, Gary H and Ryan, Patrick B and Painter, Jeffery L},
journal={KR-MED 2008},
pages={126},
year={2008}
}
Introduction to the UMLS for Text Analytics JL Painter and GH Merrill. Technical Briefing for
NC State Univeristy's Advanced Analytics Graduate Program. Presented September 12, 2007.
@inproceedings{painter2006inter,
title={Inter-translation of Biomedical Coding Schemes Using UMLS.},
author={Painter, Jeffrey L and Kleiner, Kristopher M and Merrill, Gary H},
booktitle={AAAI Fall Symposium: Semantic Web for Collaborative Knowledge Acquisition},
pages={110--111},
year={2006}
}
Curriculum Vitae 
